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    Hoffman, R.M. Three- dimensional histoculture: origins and applications in cancer research. Cancer Cells 3, 86-92, 1991. Hoffman, R.M. Visualization of GFP-expressing tumors and metastasis in vivo.BioTechnique s 30, 1016- 1026, 2001. Bouvet, M., et al. Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Res. 62, 1534- 1540, 2002. Hoffman, R.M. Green fluorescent protein imaging of tumor cells in mice. Lab Animal 31, 34-41, 2002 . Hoffman, R.M.GFP Expressing Metastatic-Cancer Mouse Models. In: Tumor Models in Cancer Research, pp. 99-112. Teicher, B., ed. Totowa, NJ: Humana Press Inc., 2002. Schmitt, C.A., et al. Dissecting p53 tumor suppressor functions in vivo. Cancer Cell 1, 289-298, 2002.
               
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    John, C.M., et al. Truncated Galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer. Clin. Cancer Res. 9, 2374-2383, 2003. Yamauchi, K., et al. Real- time in vivo dual-color imaging of intracapillary cancer cell and nucleus deformation and migration. Cancer Res. 65, 4246-4252, 2005. Amoh, Y., et al. Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function. Cell Cycle 7, 1865-1869, 2008. Hayashi, K., et al. Systemic targeting of primary bone tumor and lung met-astasis of high- grade osteosarcoma in nude mice with a tumor selective strain of Salmonella typhimurium. Cell Cycle 8,870-875, 2009. Hayashi, K., et al. Dual-color imaging of angiogenesis and its inhibition in bone and soft tissue sarcoma. J. Surg. Res. 140, 165-170, 2007. Sakuma, S., et al. In vitro/in vivo biorecognition of lectin immobil-ized fluorescent nano-spheres for human colorectal cancer cells. J Controlled Release 134, 2-10, 2009.
               
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    Gros, S.J., et al. Complementary use of fluorescence and magnetic resonance imaging of metastatic esophageal cancer in a novel orthotopic mouse model. Intl J Cancer 126, 2671-2681, 2010. Tran Cao, H.S., et al. Metronomic gemcitabine in combination with Sunitinib inhibits multisite meta-stasis and increases survival in an orthotopic model of pancreatic cancer. Mol Cancer Therap 9, 2068-2078, 2010. Kimura, H., et al. UV light killing efficacy of fluorescent protein- expressing cancer cells in vitro and in vivo. J.Cell. Biochem 110, 1439-1446, 2010. Soda, Y., et al. Transdifferen tiation of glioblastoma cells into vascular endothelial cells. Proc. Natl. Acad. Sci. USA 108, 4274- 4280, 2011. Tran Cao, H.S., et al. Submillimeter -resolution fluorescence laparoscopy of pancreatic cancer in an orthotopic mouse model visualizes metastases not seen with standard laparoscopy. J. Laparoendosc. Adv. Surg. Tech. A 21, 485-489, 2011. Hassanein, M.K., et al. Stem like and non- stem human pancreatic cancer cells distinguished by morphology and metastatic behavior. J. Cell. Biochem. 112, 3549- 3554, 2011.
               
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    Amoh, Y., et al. In vivo imaging of nuclear cyt oplasmic deformation and partition during cancer cell death due to immune rejection. J. Cell. Biochem. 113, 465- 472, 2012. Hiroshima, Y., et al. Efficacy of Salmonella typhimurium A1-R versus chemotherapy on a pancreatic cancer patient derived orthotopic xenograft (PDOX). J. Cell. Biochem. 115, 1254-1261, 2014 Maawy, A., et al. Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti carcinoembryo nic antigen antibody in a nude mouse model of human pancreatic cancer. J. Biomed. Optics 19, 101504, 2014. Matsumoto, Y., et al. Efficacy of tumor-targeting Salmonella typhimurium A1-R on nude mouse models of metastatic and disseminated human ovarian Cancer. J. Cell. Biochem. 115, 1996-2003, 2014.    
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